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Best Mosquito RepellentsFor the best mosquito bite prevention, you can't beat DEET. N,N-diethyl-3-methylbenzamide (DEET) remains the standard by which all other repellents are judged. DEET was developed by the U.S. Department of Agriculture and was registered for use by the general public in 1957. It is effective against mosquitoes, biting flies, chiggers, fleas, and ticks. Over 25 years of empirical testing of more than 20,000 other compounds has not resulted in another marketed chemical product with the duration of protection and broad-spectrum effectiveness of DEET.
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