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How Mosquitoes BiteWhen the female mosquito stabs her needle-like mouthparts through the skin of her victim, she injects her saliva -- teeming with digestive enzymes and anti-coagulants. The first time a person is bitten, there is no reaction. With subsequent mosquito bites, however, the person becomes sensitized to the foreign proteins, and small, itchy, red bumps are likely to appear about 24 hours later.
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